产品货号:
Z11616
中文名称:
ATG4C抗体
英文名称:
Anti-ATG4C Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ATG4C Antibody |
指标别名 | APG4 C;APG4C;ATG4C;AUTL1;AUTL3;Autophagin 3;Cysteine protease ATG4C |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | ATG4C |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ATG4C antibody was raised against an 18 amino acid peptide near the carboxy terminus of human ATG4C.The immunogen is located within the last 50 amino acids of ATG4C. |
计算分子量 | 52kDa |
成分 | ATG4C antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ATG4C antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Autophagy,the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells.It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2).ATG4C,also known as autophagin-3,is one of four mammalian orthologs of the yeast ATG4 protein;all four are cysteine proteases (3).Recent studies have shown that ATG4C and Beclin-1 are regulated by the microRNA miR-376b;overexpression of miR-376b led to decreased mRNA and protein levels,thereby blocking starvation and TOR inhibition-related autophagy (4). |
Uniprot ID | Q96DT6 |
基因名全称 | Autophagy related 4C,cysteine peptidase |
蛋白名全称 | Autophagy related 4C,cysteine peptidase |
推荐稀释比 | ATG4C antibody can be used for detection of ATG4C by Western blot at 1 ~ 2μg/mL.Antibody can also be used for Immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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